Pathological Expression of CXCL12 at the Blood-Brain Barrier Correlates with Severity of Multiple Sclerosis

Dysregulation of blood-brain barrier (BBB) function and transendothelial migration of leukocytes are essential components of the development and propagation of active lesions in multiple sclerosis (MS). Animal studies indicate that polarized expression of the chemokine CXCL12 at the BBB prevents leu...

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Detalhes bibliográficos
Main Authors: McCandless, Erin E., Piccio, Laura, Woerner, B. Mark, Schmidt, Robert E., Rubin, Joshua B., Cross, Anne H., Klein, Robyn S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258272/
https://ncbi.nlm.nih.gov/pubmed/18276777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070918
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