CXCL12 Mediates Trophic Interactions between Endothelial and Tumor Cells in Glioblastoma

Emerging evidence suggests endothelial cells (EC) play a critical role in promoting Glioblastoma multiforme (GBM) cell proliferation and resistance to therapy. The molecular basis for GBM-EC interactions is incompletely understood. We hypothesized that the chemokine CXCL12 and its receptor CXCR4 cou...

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Hlavní autoři: Rao, Shyam, Sengupta, Rajarshi, Choe, Eun Joo, Woerner, B. Mark, Jackson, Erin, Sun, Tao, Leonard, Jeffrey, Piwnica-Worms, David, Rubin, Joshua B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299723/
https://ncbi.nlm.nih.gov/pubmed/22427929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033005
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