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CXCL12 Alone Is Insufficient for Gliomagenesis in Nf1 Mutant Mice

Tumorigenesis requires interactions between tumor progenitors and their microenvironment. We found low cAMP levels were sufficient for tumorigenesis in a mouse model of Neurofibromatosis-1 (NF1)-associated optic pathway glioma (OPG). We hypothesized that the distinct pattern of glioma in NF1 reflect...

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Detalhes bibliográficos
Main Authors: Sun, Tao, Gianino, Scott M., Jackson, Erin, Piwnica-Worms, David, Gutmann, David H., Rubin, Joshua B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910179/
https://ncbi.nlm.nih.gov/pubmed/20554030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.05.002
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