A three-stage approach for genome-wide association studies with family data for quantitative traits

BACKGROUND: Genome-wide association (GWA) studies that use population-based association approaches may identify spurious associations in the presence of population admixture. In this paper, we propose a novel three-stage approach that is computationally efficient and robust to population admixture a...

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Main Authors: Chen, Ming-Huei, Larson, Martin G, Hsu, Yi-Hsiang, Peloso, Gina M, Guo, Chao-Yu, Fox, Caroline S, Atwood, Larry D, Yang, Qiong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892427/
https://ncbi.nlm.nih.gov/pubmed/20470424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-40
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