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Rad8(Rad5)/Mms2–Ubc13 ubiquitin ligase complex controls translesion synthesis in fission yeast
Many DNA lesions cause pausing of replication forks at lesion sites; thus, generating gaps in the daughter strands that are filled-in by post-replication repair (PRR) pathways. In Saccharomyces cerevisiae, PRR involves translesion synthesis (TLS) mediated by Polη or Polζ, or Rad5-dependent gap filli...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892369/ https://ncbi.nlm.nih.gov/pubmed/20453833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.87 |
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