Human SHPRH is a ubiquitin ligase for Mms2–Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen

Human SHPRH gene is located at the 6q24 chromosomal region, and loss of heterozygosity in this region is seen in a wide variety of cancers. SHPRH is a member of the SWI/SNF family of ATPases/helicases, and it possesses a C(3)HC(4) RING motif characteristic of ubiquitin ligase proteins. In both of th...

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Bibliographic Details
Main Authors: Unk, Ildiko, Hajdú, Ildikó, Fátyol, Károly, Szakál, Barnabás, Blastyák, András, Bermudez, Vladimir, Hurwitz, Jerard, Prakash, Louise, Prakash, Satya, Haracska, Lajos
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838714/
https://ncbi.nlm.nih.gov/pubmed/17108083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608595103
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