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A Femtomol Range FRET Biosensor Reports Exceedingly Low Levels of Cell Surface Furin: Implications for the Processing of Anthrax Protective Antigen

Furin, a specialized endoproteinase, transforms proproteins into biologically active proteins. Furin function is important for normal cells and also in multiple pathologies including malignancy and anthrax. Furin is believed to cycle between the Golgi compartment and the cell surface. Processing of...

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Bibliografiska uppgifter
Huvudupphovsmän: Gawlik, Katarzyna, Remacle, Albert G., Shiryaev, Sergey A., Golubkov, Vladislav S., Ouyang, Mingxing, Wang, Yingxiao, Strongin, Alex Y.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892035/
https://ncbi.nlm.nih.gov/pubmed/20585585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011305
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