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Cryptococcus neoformans responds to mannitol by increasing capsule size in vitro and in vivo

The polysaccharide capsule of the fungus Cryptococcus neoformans is its main virulence factor. In this study, we determined the effects of mannitol and glucose on the capsule and exopolysaccharide production. Growth in mannitol significantly increased capsular volume compared to cultivation in gluco...

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Detalhes bibliográficos
Main Authors: Guimarães, Allan Jefferson, Frases, Susana, Cordero, Radamés J. B., Nimrichter, Leonardo, Casadevall, Arturo, Nosanchuk, Joshua D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891871/
https://ncbi.nlm.nih.gov/pubmed/20070311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01430.x
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