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Cryptococcus neoformans responds to mannitol by increasing capsule size in vitro and in vivo

The polysaccharide capsule of the fungus Cryptococcus neoformans is its main virulence factor. In this study, we determined the effects of mannitol and glucose on the capsule and exopolysaccharide production. Growth in mannitol significantly increased capsular volume compared to cultivation in gluco...

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Autors principals: Guimarães, Allan Jefferson, Frases, Susana, Cordero, Radamés J. B., Nimrichter, Leonardo, Casadevall, Arturo, Nosanchuk, Joshua D.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891871/
https://ncbi.nlm.nih.gov/pubmed/20070311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01430.x
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