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Cryptococcus neoformans responds to mannitol by increasing capsule size in vitro and in vivo

The polysaccharide capsule of the fungus Cryptococcus neoformans is its main virulence factor. In this study, we determined the effects of mannitol and glucose on the capsule and exopolysaccharide production. Growth in mannitol significantly increased capsular volume compared to cultivation in gluco...

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Bibliographic Details
Main Authors: Guimarães, Allan Jefferson, Frases, Susana, Cordero, Radamés J. B., Nimrichter, Leonardo, Casadevall, Arturo, Nosanchuk, Joshua D.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891871/
https://ncbi.nlm.nih.gov/pubmed/20070311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2010.01430.x
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