Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ(3)

During early pregnancy, placentation occurs in a relatively hypoxic environment that is essential for appropriate embryonic development. Intervillous blood flow increases around 10 to 12 weeks of gestation and results in exposure of trophoblast cells to increased oxygen tension. Before this time, lo...

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Opis bibliograficzny

Wydane w:	J Clin Invest
Główni autorzy:	Caniggia, Isabella, Mostachfi, Homa, Winter, Jennifer, Gassmann, Max, Lye, Stephen J., Kuliszewski, Maciej, Post, Martin
Format:	Artigo
Język:	Inglês
Wydane:	American Society for Clinical Investigation 2000
Hasła przedmiotowe:	Article
Dostęp online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10712429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8316
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