CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis

Experimental autoimmune glomerulonephritis (EAG), an animal model of Goodpasture’s disease, can be induced in Wistar Kyoto (WKY) rats by a single injection of rat glomerular basement membrane (GBM) in adjuvant. EAG is characterized by circulating and deposited anti-GBM antibodies, accompanied by foc...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Reynolds, John, Tam, Frederick W.K., Chandraker, Anil, Smith, Jennifer, Karkar, Ayman M., Cross, Jane, Peach, Robert, Sayegh, Mohamed H., Pusey, Charles D.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289170/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10712436/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI6710
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