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The role of the LDL receptor in apolipoprotein B secretion

Familial hypercholesterolemia is caused by mutations in the LDL receptor gene (Ldlr). Elevated plasma LDL levels result from slower LDL catabolism and a paradoxical lipoprotein overproduction. We explored the relationship between the presence of the LDL receptor and lipoprotein secretion in hepatocy...

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Detalhes bibliográficos
Main Authors: Twisk, Jaap, Gillian-Daniel, Donald L., Tebon, Angie, Wang, Lin, Barrett, P. Hugh R., Attie, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC289165/
https://ncbi.nlm.nih.gov/pubmed/10683382
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