Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

Lipopolysaccharide (LPS) is the main inducer of shock and death in Gram-negative sepsis. Recent evidence suggests that LPS-induced signal transduction begins with CD14-mediated activation of 1 or more Toll-like receptors (TLRs). The lipid A analogues lipid IVa and Rhodobacter sphaeroides lipid A (RS...

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Autors principals: Lien, Egil, Means, Terry K., Heine, Holger, Yoshimura, Atsutoshi, Kusumoto, Shoichi, Fukase, Koichi, Fenton, Matthew J., Oikawa, Masato, Qureshi, Nilofer, Monks, Brian, Finberg, Robert W., Ingalls, Robin R., Golenbock, Douglas T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2000
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC289161/
https://ncbi.nlm.nih.gov/pubmed/10683379
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