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Stereoselective Synthesis of a C-linked Neuraminic Acid Disaccharide: Potential Building Block for the Synthesis of C-Analogs of Polysialic acids

[Image: see text] C-Linked neuraminic acid disaccharide was synthesized in a diastereoselective manner from a sulfone donor and aldehyde acceptor, which was protected as propargyl ether, through a samarium mediated coupling reaction. The resulting disaccharide has acetal and phenyl sulfide functiona...

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Detalhes bibliográficos
Main Authors: Kim, Jin-Hwan, Huang, Fei, Ly, Mellisa, Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891570/
https://ncbi.nlm.nih.gov/pubmed/19006371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo801946y
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