Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation

Autophagy is an evolutionarily conserved cell survival pathway that enables cells to recoup ATP and other critical biosynthetic molecules during nutrient deprivation or exposure to hypoxia, which are hallmarks of the tumour microenvironment. Autophagy has been implicated as a potential mechanism of...

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Detalhes bibliográficos
Main Authors: Carew, Jennifer S, Medina, Ernest C, Esquivel II, Juan A, Mahalingam, Devalingam, Swords, Ronan, Kelly, Kevin, Zhang, Hui, Huang, Peng, Mita, Alain C, Mita, Monica M, Giles, Francis J, Nawrocki, Steffan T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891399/
https://ncbi.nlm.nih.gov/pubmed/19583815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00832.x
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