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T(2) relaxation times of (13)C metabolites in a rat hepatocellular carcinoma model measured in vivo using (13)C-MRS of hyperpolarized [1-(13)C]pyruvate

A single-voxel Carr-Purcell-Meibloom-Gill sequence was developed to measure localized T(2) relaxation times of (13)C-labeled metabolites in vivo for the first time. Following hyperpolarized [1-(13)C]pyruvate injections, pyruvate and its metabolic products, alanine and lactate, were observed in the l...

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Hlavní autoři: Yen, Yi-Fen, Le Roux, Patrick, Mayer, Dirk, King, Randy, Spielman, Daniel, Tropp, James, Pauly, Kim Butts, Pfefferbaum, Adolf, Vasanawala, Shreyas, Hurd, Ralph
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891253/
https://ncbi.nlm.nih.gov/pubmed/20175135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1481
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