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Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors
The synthesis and structure–activity relationship analysis of a novel class of amide-based biaryl NR2B-selective NMDA receptor antagonists are presented. Some of the studied compounds are potent, selective, non-competitive, and voltage-independent antagonists of NR2B-containing NMDA receptors. Like...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , , , , , , , |
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| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
2009
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891242/ https://ncbi.nlm.nih.gov/pubmed/19648014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.05.085 |
| ট্যাগগুলো: |
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