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Characterization of Aziridinylbenzoquinone DNA Cross-links by LC-IRMPD-MS
DNA cross-linking was evaluated by LC-MS/MS to determine the relative cross-linking abilities of two aziridinylbenzoquinones. Reactivities of RH1 (2,5-diaziridinyl-3-[hydroxymethyl]-6-methyl-1,4-benzoquinone), a clinically studied anti-tumor cross-linking agent, and an analog containing a phenyl gro...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891125/ https://ncbi.nlm.nih.gov/pubmed/20369834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx1000738 |
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