Mixed-Isotope Labeling with LC-IMS-MS for Characterization of Protein-Protein Interactions by Chemical Cross-Linking

Chemical cross-linking of proteins followed by proteolysis and mass spectrometric analysis of the resulting cross-linked peptides provides powerful insight into the quaternary structure of protein complexes. Mixed-isotope cross-linking (a method for distinguishing intermolecular cross-links) was cou...

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Main Authors: Merkley, Eric D., Baker, Erin S., Crowell, Kevin L., Orton, Daniel J., Taverner, Thomas, Ansong, Charles, Ibrahim, Yehia M., Burnet, Meagan C., Cort, John R., Anderson, Gordon A., Smith, Richard D., Adkins, Joshua N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594340/
https://ncbi.nlm.nih.gov/pubmed/23423792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-012-0565-x
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