An LC-IMS-MS Platform Providing Increased Dynamic Range for High-Throughput Proteomic Studies

A high-throughput approach and platform using 15 minute reversed-phase capillary liquid chromatography (RPLC) separations in conjunction with ion mobility spectrometry-mass spectrometry (IMS-MS) measurements was evaluated for the rapid analysis of complex proteomics samples. To test the separation q...

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Main Authors: Baker, Erin Shammel, Livesay, Eric A., Orton, Daniel J., Moore, Ronald J., Danielson, William F., Prior, David C., Ibrahim, Yehia M., LaMarche, Brian L., Mayampurath, Anoop M., Schepmoes, Athena A., Hopkins, Derek F., Tang, Keqi, Smith, Richard D., Belov, Mikhail E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819092/
https://ncbi.nlm.nih.gov/pubmed/20000344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr900888b
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