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Fully automated, four-column capillary LC-MS system for maximizing throughput in proteomic analyses

We describe a 4-column, high-pressure capillary liquid chromatography (LC) system for robust, high-throughput LC-MS(/MS) analyses. This system performs multiple LC separations in parallel, but staggers each of them such that the data-rich region of each separation is sampled sequentially. By allowin...

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Bibliographische Detailangaben
Hauptverfasser: Livesay, Eric A., Tang, Keqi, Taylor, Beverley K., Buschbach, Michael A., Hopkins, Derek F., LaMarche, Brian L., Zhao, Rui, Shen, Yufeng, Orton, Daniel J., Moore, Ronald J., Kelly, Ryan T., Udseth, Harold R., Smith, Richard D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516349/
https://ncbi.nlm.nih.gov/pubmed/18044960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac701727r
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