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Rapid Characterization of Cross-links, Mono-adducts, and Non-covalent Binding of Psoralens to Deoxyoligonucleotides by LC-UV/ESI-MS and IRMPD Mass Spectrometry
Upon UV photoactivation, psoralen analogs form covalent mono-adducts and cross-links with DNA at thymine residues. Electrospray ionization mass spectrometric analysis allowed rapid and efficient determination of the reaction percentages of each psoralen analog with DNA duplexes containing different...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890229/ https://ncbi.nlm.nih.gov/pubmed/20419242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b924023c |
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