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The C8-2′-Deoxyguanosine Adduct of 2-Amino-3-methylimidazo[1,2-d]naphthalene, a Carbocyclic Analogue of the Potent Mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ), is a Block to Replication in Vitro

2-Amino-3-methylimidazo[4,5-f]naphthelene is a carbocyclic analogue of the dietary carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in which a naphthalene ring system replaces the quinoline unit of IQ. The activity of 2-amino-3-methylimidazo[4,5-f]naphthelene (cIQ) in Ames Salmonella typhimur...

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Main Authors: Christov, Plamen P., Chowdhury, Goutam, Garmendia, Craig A., Wang, Feng, Stover, James S., Elmquist, C. Eric, Kozekova, Albena, Angel, Karen C., Turesky, Robert J., Stone, Michael P., Guengerich, F. Peter, Rizzo, Carmelo J.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891123/
https://ncbi.nlm.nih.gov/pubmed/20377178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100053n
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