The C8-2′-Deoxyguanosine Adduct of 2-Amino-3-methylimidazo[1,2-d]naphthalene, a Carbocyclic Analogue of the Potent Mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ), is a Block to Replication in Vitro

2-Amino-3-methylimidazo[4,5-f]naphthelene is a carbocyclic analogue of the dietary carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in which a naphthalene ring system replaces the quinoline unit of IQ. The activity of 2-amino-3-methylimidazo[4,5-f]naphthelene (cIQ) in Ames Salmonella typhimur...

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Main Authors: Christov, Plamen P., Chowdhury, Goutam, Garmendia, Craig A., Wang, Feng, Stover, James S., Elmquist, C. Eric, Kozekova, Albena, Angel, Karen C., Turesky, Robert J., Stone, Michael P., Guengerich, F. Peter, Rizzo, Carmelo J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891123/
https://ncbi.nlm.nih.gov/pubmed/20377178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100053n
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