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Evolution of class-specific peptides targeting a hot spot of the Gαs subunit
The four classes of heterotrimeric G protein α subunits act as molecular routers inside cells, gating signals based on a bound guanosine nucleotide (GTP vs. GDP). Ligands that specifically target individual subunits provide new tools to monitor and modulate these networks, but are challenging to des...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891084/ https://ncbi.nlm.nih.gov/pubmed/18329041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.032 |
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