Mutant presenilin-1 deregulated peripheral immunity exacerbates Alzheimer-like pathology

Mutations in the presenilin-1 (PS1) gene are independent causes of familial Alzheimer's disease (AD). AD patients have dysregulated immunity, and PS1 mutant mice exhibit abnormal systemic immune responses. To test whether immune function abnormality caused by a mutant human PS1 gene (mhPS1) cou...

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Xehetasun bibliografikoak
Egile Nagusiak: Zhu, Yuyan, Obregon, Demian, Hou, Huayan, Giunta, Brian, Ehrhart, Jared, Fernandez, Frank, Mori, Takashi, Nikolic, William, Zhao, Yangbing, Morgan, Dave, Town, Terrence, Tan, Jun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Publishing Ltd 2011
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891003/
https://ncbi.nlm.nih.gov/pubmed/19900216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00962.x
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