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Construction and characterization of calreticulin-HBsAg fusion gene recombinant adenovirus expression vector

AIM: To generate recombinant adenoviral vector containing calreticulin (CRT)-hepatitis B surface antigen (HBsAg) fusion gene for developing a safe, effective and HBsAg-specific therapeutic vaccine. METHODS: CRT and HBsAg gene were fused using polymerase chain reaction (PCR), endonuclease digestion a...

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Detalhes bibliográficos
Main Authors: Ma, Chun-Ling, Wang, Gui-Bin, Gu, Run-Guo, Wang, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890950/
https://ncbi.nlm.nih.gov/pubmed/20572313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i24.3078
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