Lentivector expressing HBsAg and immunoglobulin Fc fusion antigen induces potent immune responses and results in seroconversion in HBsAg transgenic mice

Even though hepatitis B virus (HBV) vaccines effectively prevent new cases of HBV infection, with approximately 350 million patients worldwide, chronic HBV infection remains a major health problem because of the associated complications (such as liver cirrhosis and hepatocellular carcinoma) and the...

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Main Authors: Hong, Yuan, Peng, Yibing, Mi, Michael, Munn, David H, Wang, Gui-qiang, He, Yukai
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090480/
https://ncbi.nlm.nih.gov/pubmed/21421003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.03.025
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