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WASH and WAVE actin regulators of the Wiskott–Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

We recently showed that the Wiskott–Aldrich syndrome protein (WASP) family member, WASH, localizes to endosomal subdomains and regulates endocytic vesicle scission in an Arp2/3-dependent manner. Mechanisms regulating WASH activity are unknown. Here we show that WASH functions in cells within a 500 k...

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Autors principals: Jia, Da, Gomez, Timothy S., Metlagel, Zoltan, Umetani, Junko, Otwinowski, Zbyszek, Rosen, Michael K., Billadeau, Daniel D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890800/
https://ncbi.nlm.nih.gov/pubmed/20498093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913293107
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