Actin-bound structures of Wiskott–Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly

Wiskott–Aldrich syndrome protein (WASP)-homology domain 2 (WH2) is a small and widespread actin-binding motif. In the WASP family, WH2 plays a role in filament nucleation by Arp2/3 complex. Here we describe the crystal structures of complexes of actin with the WH2 domains of WASP, WASP-family verpro...

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Detalhes bibliográficos
Main Authors: Chereau, David, Kerff, Frederic, Graceffa, Philip, Grabarek, Zenon, Langsetmo, Knut, Dominguez, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283820/
https://ncbi.nlm.nih.gov/pubmed/16275905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507021102
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