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Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members

The cadherin superfamily encodes more than 100 receptors with diverse functions in tissue development and homeostasis. Classical cadherins mediate adhesion by binding interactions that depend on their N-terminal extracellular cadherin (EC) domains, which swap N-terminal β-strands. Sequence alignment...

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Bibliografiske detaljer
Main Authors: Elledge, Heather M., Kazmierczak, Piotr, Clark, Peter, Joseph, Jeremiah S., Kolatkar, Anand, Kuhn, Peter, Müller, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890781/
https://ncbi.nlm.nih.gov/pubmed/20498078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006284107
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