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The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions

Usher syndrome type 1 (USH1) patients suffer from sensorineuronal deafness, vestibular dysfunction, and visual impairment. Several genetic loci have been linked to USH1, and four of the relevant genes have been identified. They encode the unconventional myosin VIIa, the PDZ-domain protein harmonin,...

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Detalhes bibliográficos
Main Authors: Siemens, Jan, Kazmierczak, Piotr, Reynolds, Anna, Sticker, Melanie, Littlewood-Evans, Amanda, Müller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137525/
https://ncbi.nlm.nih.gov/pubmed/12407180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232579599
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