Development and Regeneration of Sensory Transduction in Auditory Hair Cells Requires Functional Interaction Between Cadherin-23 and Protocadherin-15

Tip links are extracellular filaments that connect pairs of hair cell stereocilia and convey tension to mechanosensitive channels. Recent evidence suggests that tip links are formed by calcium-dependent interactions between the N-terminal domains of cadherin-23 (CDH23) and protocadherin-15 (PCDH15)....

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Main Authors: Lelli, Andrea, Kazmierczak, Piotr, Kawashima, Yoshiyuki, Müller, Ulrich, Holt, Jeffrey R.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949085/
https://ncbi.nlm.nih.gov/pubmed/20739546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1949-10.2010
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