Potent anti-tumor activity of telomerase-dependent and HSV-TK armed oncolytic adenovirus for non-small cell lung cancer in vitro and in vivo

BACKGROUND: Non-small cell lung cancer (NSCLC) is the leading cause of cancer related mortality, any improvements in therapeutic strategies are urgently required. In this study we generated a novel 'suicide gene' armed oncolytic adenoviral vector and investigated its antitumor effect both...

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Autors principals: Zhang, Ju-Feng, Wei, Fang, Wang, Hui-Ping, Li, Hui-Ming, Qiu, Wei, Ren, Peng-Kang, Chen, Xia-Fang, Huang, Qian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890545/
https://ncbi.nlm.nih.gov/pubmed/20487549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-52
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