Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection

HIV-1 invades the central nervous system (CNS) in the context of acute infection, persists thereafter in the absence of treatment, and leads to chronic intrathecal immunoactivation that can be measured by the macrophage activation marker, neopterin, in cerebrospinal fluid (CSF). In this review we de...

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Bibliographische Detailangaben
Hauptverfasser: Hagberg, Lars, Cinque, Paola, Gisslen, Magnus, Brew, Bruce J, Spudich, Serena, Bestetti, Arabella, Price, Richard W, Fuchs, Dietmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890504/
https://ncbi.nlm.nih.gov/pubmed/20525234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-7-15
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