Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection

HIV-1 invades the central nervous system (CNS) in the context of acute infection, persists thereafter in the absence of treatment, and leads to chronic intrathecal immunoactivation that can be measured by the macrophage activation marker, neopterin, in cerebrospinal fluid (CSF). In this review we de...

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Bibliografiske detaljer
Main Authors: Hagberg, Lars, Cinque, Paola, Gisslen, Magnus, Brew, Bruce J, Spudich, Serena, Bestetti, Arabella, Price, Richard W, Fuchs, Dietmar
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890504/
https://ncbi.nlm.nih.gov/pubmed/20525234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-7-15
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