Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection

HIV-1 invades the central nervous system (CNS) in the context of acute infection, persists thereafter in the absence of treatment, and leads to chronic intrathecal immunoactivation that can be measured by the macrophage activation marker, neopterin, in cerebrospinal fluid (CSF). In this review we de...

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Detalhes bibliográficos
Main Authors: Hagberg, Lars, Cinque, Paola, Gisslen, Magnus, Brew, Bruce J, Spudich, Serena, Bestetti, Arabella, Price, Richard W, Fuchs, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890504/
https://ncbi.nlm.nih.gov/pubmed/20525234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-7-15
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