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Activation of dormant ovarian follicles to generate mature eggs
Although multiple follicles are present in mammalian ovaries, most of them remain dormant for years or decades. During reproductive life, some follicles are activated for development. Genetically modified mouse models with oocyte-specific deletion of genes in the PTEN-PI3K-Akt-Foxo3 pathway exhibite...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890455/ https://ncbi.nlm.nih.gov/pubmed/20479243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001198107 |
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