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Activation of dormant ovarian follicles to generate mature eggs

Although multiple follicles are present in mammalian ovaries, most of them remain dormant for years or decades. During reproductive life, some follicles are activated for development. Genetically modified mouse models with oocyte-specific deletion of genes in the PTEN-PI3K-Akt-Foxo3 pathway exhibite...

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Autori principali: Li, Jing, Kawamura, Kazuhiro, Cheng, Yuan, Liu, Shuang, Klein, Cynthia, Liu, Shu, Duan, En-Kui, Hsueh, Aaron J. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890455/
https://ncbi.nlm.nih.gov/pubmed/20479243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001198107
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