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Activation of dormant ovarian follicles to generate mature eggs

Although multiple follicles are present in mammalian ovaries, most of them remain dormant for years or decades. During reproductive life, some follicles are activated for development. Genetically modified mouse models with oocyte-specific deletion of genes in the PTEN-PI3K-Akt-Foxo3 pathway exhibite...

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Bibliografiske detaljer
Main Authors: Li, Jing, Kawamura, Kazuhiro, Cheng, Yuan, Liu, Shuang, Klein, Cynthia, Liu, Shu, Duan, En-Kui, Hsueh, Aaron J. W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890455/
https://ncbi.nlm.nih.gov/pubmed/20479243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001198107
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