Učitavanje...
Shear stress, SIRT1, and vascular homeostasis
Shear stress imposed by blood flow is crucial for maintaining vascular homeostasis. We examined the role of shear stress in regulating SIRT1, an NAD(+)-dependent deacetylase, and its functional relevance in vitro and in vivo. The application of laminar flow increased SIRT1 level and activity, mitoch...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890429/ https://ncbi.nlm.nih.gov/pubmed/20479254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003833107 |
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