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Systems biology analysis of longitudinal functional response of endothelial cells to shear stress

Blood flow and vascular shear stress patterns play a significant role in inducing and modulating physiological responses of endothelial cells (ECs). Pulsatile shear (PS) is associated with an atheroprotective endothelial phenotype, while oscillatory shear (OS) is associated with an atheroprone endot...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ajami, Nassim E., Gupta, Shakti, Maurya, Mano R., Nguyen, Phu, Li, Julie Yi-Shuan, Shyy, John Y.-J., Chen, Zhen, Chien, Shu, Subramaniam, Shankar
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642700/
https://ncbi.nlm.nih.gov/pubmed/28973892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707517114
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