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The Oral Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Increases Circulating Endothelial Progenitor Cells in Patients With Type 2 Diabetes: Possible role of stromal-derived factor-1α
OBJECTIVE: Vasculoprotective endothelial progenitor cells (EPCs) are regulated by stromal-derived factor-1α (SDF-1α) and are reduced in type 2 diabetes. Because SDF-1α is a substrate of dipeptidyl-peptidase-4 (DPP-4), we investigated whether the DPP-4 inhibitor sitagliptin modulates EPC levels in ty...
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Autori principali: | , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Diabetes Association
2010
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890368/ https://ncbi.nlm.nih.gov/pubmed/20357375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc10-0187 |
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