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The dipeptidyl peptidase-4 inhibitor Saxagliptin improves function of circulating pro-angiogenic cells from type 2 diabetic patients

BACKGROUND: Type 2 diabetes (T2D) is associated with reduction and dysfunction of circulating pro-angiogenic cells (PACs). DPP-4 inhibitors, a class of oral agents for T2D, might possess pleiotropic vasculoprotective activities. Herein, we tested whether DPP-4 inhibition with Saxagliptin affects the...

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Detalhes bibliográficos
Main Authors: Poncina, Nicol, Albiero, Mattia, Menegazzo, Lisa, Cappellari, Roberta, Avogaro, Angelo, Fadini, Gian Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033689/
https://ncbi.nlm.nih.gov/pubmed/24886621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-92
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