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Native and recombinant ASIC1a receptors conduct negligible Ca(2+) entry

Acid Sensing Ion Channels (ASICs) are a family of proton-gated cation channels that play a role in the sensation of noxious stimuli. Of these, ASIC1a is the only family member that is reported to be permeable to Ca(2+), although the absolute magnitude of the Ca(2+) current is unclear. Here, we used...

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Autori principali: Samways, Damien S.K., Harkins, Amy B., Egan, Terrance M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890224/
https://ncbi.nlm.nih.gov/pubmed/19185346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2008.12.002
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