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In vivo targeting of B-cell lymphoma with glycan ligands of CD22

Antibody-mediated cell depletion therapy has proven to provide significant clinical benefit in treatment of lymphomas and leukemias, driving the development of improved therapies with novel mechanisms of cell killing. A current clinical target for B-cell lymphoma is CD22, a B-cell–specific member of...

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Autori principali: Chen, Weihsu C., Completo, Gladys C., Sigal, Darren S., Crocker, Paul R., Saven, Alan, Paulson, James C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890185/
https://ncbi.nlm.nih.gov/pubmed/20181615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-257386
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