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Supramolecular Complexing of Membane Siglec CD22 Mediated by a Polyvalent Heterobifunctional Ligand that Templates on IgM

We report the synthesis and in vitro evaluation of a multivalent homing device, a polymer which contains pre-ordered pendant groups with dual specificity, a trisaccharide moiety, which is specific for the siglec CD22, and an antibody specific hapten, nitrophenol. The device efficiently attracts anti...

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Detalles Bibliográficos
Main Authors: Cui, Lina, Kitov, Pavel I., Completo, Gladys C., Paulson, James C., Bundle, David R.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086123/
https://ncbi.nlm.nih.gov/pubmed/21405019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100579d
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