Screening of Complement Inhibitors: Shielded Baculoviruses Increase the Safety and Efficacy of Gene Delivery

One of the major obstacles in the use of baculovirus vectors for in vivo gene transfer is the virus inactivation by serum complement. In this study, we investigated the effect of decay-accelerating factor (DAF), factor H (FH)–like protein-1 (FHL-1), C4b-binding protein (C4BP), and membrane cofactor...

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Detaylı Bibliyografya
Asıl Yazarlar: Kaikkonen, Minna U, Maatta, Antti I, Ylä-Herttuala, Seppo, Airenne, Kari J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2010
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890102/
https://ncbi.nlm.nih.gov/pubmed/20179675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.25
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