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Screening of Complement Inhibitors: Shielded Baculoviruses Increase the Safety and Efficacy of Gene Delivery
One of the major obstacles in the use of baculovirus vectors for in vivo gene transfer is the virus inactivation by serum complement. In this study, we investigated the effect of decay-accelerating factor (DAF), factor H (FH)–like protein-1 (FHL-1), C4b-binding protein (C4BP), and membrane cofactor...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890102/ https://ncbi.nlm.nih.gov/pubmed/20179675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.25 |
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