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Manipulation of Death Pathways in Desmin Related Cardiomyopathy

RATIONALE: Transgenic mice with cardiac specific overexpression of mutated αB-crystallin (CryAB(R120G)) display Desmin Related Myopathy (DRM) with dilated cardiomyopathy and heart failure. Our previous studies showed the presence of progressive mitochondrial abnormalities and activation of apoptotic...

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Bibliografiska uppgifter
Huvudupphovsmän: Maloyan, Alina, Sayegh, Jennifer, Osinska, Hanna, Chua, Balvin H.L., Robbins, Jeffrey
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890082/
https://ncbi.nlm.nih.gov/pubmed/20360253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.212639
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